Search results for " large bowel"

showing 4 items of 4 documents

Lactobacillus casei and Bifidobacterium lactis supplementation reduces tissue damage of intestinal mucosa and liver after 2,4,6-trinitrobenzenesulfon…

2014

Probiotics (PB) are living microorganisms that act as a commensal population in normal intestines and confer numerous beneficial effects on the host. The introduction of probiotics in the treatment of inflammatory bowel disease (IBD) prolongs remission. The aim of this study was to investigate the intestinal and hepatic effects of PB supplementation in an experimental IBD model in mice induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS). In the first step of the experimental procedure, CD-1 male mice, 5 to 6 weeks old, were randomly divided into 3 groups and inoculated intrarectally with, respectively, saline, alcohol, or TNBS to assess the experimental IBD model. In the second step, mice…

MaleLacticaseibacillus caseiMiceLiverTrinitrobenzenesulfonic AcidProbioticsDietary SupplementsAnimalsHumansBifidobacteriumIntestinal MucosaInflammatory Bowel DiseasesIntestinal Inflammation intestinal cancer microbiotaprobiotic supplementation large bowel liver apoptosis
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HSP60 IS THE MOST PREDICTIVE HEAT SHOCK PROTEIN DURING LARGE BOWEL CARCINOGENESIS

2014

Hsp 60 Large Bowel Exosomes.
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Clinical strategies for the management of intestinal obstruction and pseudo-obstruction. A Delphi Consensus study of SICUT (Società Italiana di Chiru…

2016

Intestinal obstructions/pseudo-obstruction of the small/large bowel are frequent conditions but their management could be challenging. Moreover, a general agreement in this field is currently lacking, thus SICUT Society designed a consensus study aimed to define their optimal workout.The Delphi methodology was used to reach consensus among 47 Italian surgical experts in two study rounds. Consensus was defined as an agreement of 75.0% or greater. Four main topic areas included nosology, diagnosis, management and treatment.A bowel obstruction was defined as an obstacle to the progression of intestinal contents and fluids generally beginning with a sudden onset. The panel identified four major…

HerniaDelphi TechniqueContrast MediaAcidosis; Conservative Treatment; Contrast Media; Delphi Technique; Diatrizoate Meglumine; Disease Management; Emergencies; Emergency Medicine; General Surgery; Hernia; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Intubation Gastrointestinal; Laparotomy; Societies Medical; Stents; Symptom Assessment; Tomography X-Ray ComputedConservative TreatmentStentHumansLarge bowel obstructionIntubation GastrointestinalSocieties MedicalDiatrizoate MeglumineEmergencieLaparotomyIntestinal Pseudo-ObstructionDisease ManagementSmall bowelDelphi study Intestinal obstruction Large bowel obstruction Pseudo-obstruction Small bowelDelphi studyAcidosiGeneral SurgeryEmergency MedicineStentsEmergenciesSymptom AssessmentAcidosisTomography X-Ray ComputedPseudo-obstructionIntestinal ObstructionHuman
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Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of lar…

2016

Large bowel carcinogenesis involves accumulation of genetic alterations leading to transformation of normal mucosa into dysplasia and, lastly, adenocarcinoma. It is pertinent to elucidate the molecular changes occurring in the pre-neoplastic lesions to facilitate early diagnosis and treatment. Heat shock proteins (Hsps), many of which are molecular chaperones, are implicated in carcinogenesis, and their variations with tumor progression encourage their study as biomarkers. There are many reports on Hsps and cancer but none to our knowledge on their systematic quantification in pre-neoplastic lesions of the large bowel. We performed immunohistochemical determinations of Hsp10, Hsp60, Hsp70, …

0301 basic medicineAdenomaMaleDysplasiaPathologymedicine.medical_specialtyColorectal cancerColonLarge bowelChaperoneBiologyAdenocarcinomamedicine.disease_causeBiochemistryMitochondrial Proteins03 medical and health sciencesBiomarker; Chaperone; Dysplasia; Hsps; Large bowel; Tubular adenoma; Biochemistry; Cell Biology0302 clinical medicineTubular adenomaHeat shock proteinmedicineBiomarkers TumorChaperonin 10HspHumansIntestinal MucosaEarly Detection of CancerAgedTubular adenomaAged 80 and overLamina propriaOriginal PaperBiomarkerCell BiologyChaperonin 60Middle Agedmedicine.disease030104 developmental biologymedicine.anatomical_structureDysplasiaTumor progression030220 oncology & carcinogenesisCase-Control StudiesImmunologyAdenocarcinomaFemaleCarcinogenesisColorectal Neoplasms
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